Antimicrobial Blue Light Inactivation of Microbial Isolates in Biofilms

Microbial inactivation properties of a new antimicrobial/antithrombotic catheter lock solution (citrate/methylene blue/parabens)

BACKGROUND Microbial infections are the most serious complications associated with indwelling central venous catheters. A catheter lock solution that is both antibacterial and antithrombotic is needed. The goal of this study was to determine whether a new catheter lock solution containing citrate, methylene blue and parabens has antimicrobial properties against planktonic bacteria and against s...

Blue light-mediated inactivation of Enterococcus faecalis in vitro.

In dentistry, residual infection remains a major cause of failure after endodontic treatment; many of these infections involve Enterococcus faecalis. In the current study, we explored the possibility that blue light activated photosensitizers could be used, in principle, to inactivate this microbe as an adjunct disinfection strategy for endodontic therapy. Three blue light absorbing photosensit...

Microbial biofilms and their control by various antimicrobial strategies

In nature, bacteria as opposed to the planktonic form predominantly exist as biofilms. Biofilms are consortium of microorganisms and can be considered as complex communities of microorganisms which are embedded in a selfproduced matrix of extracellular polymeric substances attached to a substratum which can be inert or living surfaces. In the recent years, there is an increasing interest in stu...

Microbial Biofilms

Antimicrobial resistance in biofilms

The ability of microorganisms to form biofilms is closely related to infectious diseases, and environmental and biotechnological processes. Biofilms constituting a microbial multicellular lifestyle and are defined as organized communities of bacteria, collaborating among themselves and being attached to an inert or living surface contained in a self-produced polymeric matrix made principally of...